DRUG INTERACTIONS
But if you have certain medical conditions or are taking other drugs, your doctor may recommend that you take this drug less often than once a day.
| Parameter | Value | Description |
|---|---|---|
| Half-life | 4 hours | Time to reduce plasma concentration by half |
| Maximum plasma concentration | 0.8-1.5 hours | Peak effect timing |
| Absorption rate | Rapid, within 30-60 minutes | After oral administration |
It is important to note that certain foods, particularly foods high in fat, can cause the drug to work more slowly than normal.
What special precautions should I follow?
Sildenafil oral tablet is available as a brand-name drug and as a generic drug. Sildenafil comes in three forms: an oral tablet, an oral suspension (liquid), and an injection that’s only given by a doctor. Sildenafil oral tablet is used to treat erectile dysfunction (ED). It’s also used to treat pulmonary arterial hypertension (PAH). It comes in the form of a tablet and suspension (liquid).
Addyi (filbanserin)
It also comes in an intravenous (IV) form, which is only given by a doctor. Sildenafil oral tablet is available as the brand-name drugs Viagra and Revatio. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. Sildenafil oral tablet doesn’t cause drowsiness, but it can cause other side effects, including: flushing (reddening and warming of the face) an erection that lasts longer than normal If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk with your doctor or pharmacist. Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency.
- Patients should avoid grapefruit or grapefruit juice while taking sildenafil tablets.
- Consult your doctor if you experience persistent pain or vision changes.
- Sildenafil tablets can be part of a broader treatment plan including lifestyle changes.
Serious side effects and their symptoms can include the following: Symptoms can include:blurry visionconfusiondizzinessfaintinglightheadednessnausea or vomitingsleepinessweakness Increased shortness of breath or trouble breathing Priapism (an erection that lasts more than 4 hours) Symptoms can include:sudden vision loss in one or both eyes sudden vision loss in one or both eyes Symptoms can include:sudden hearing losstinnitus (ringing in your ears)dizziness Heart problems, such as heart attack, stroke, or irregular heart rate. Symptoms can include:chest painshortness of breathdizzinesstrouble speakingconfusionnausea or vomitingfeeling lightheaded Priapism warning: This drug can cause priapism, which is an erection that won’t go away. If you have an erection that lasts more than 4 hours, call 911 or go to the nearest emergency room.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Viagra Generic | 25mg | 270 + 8 Pills | 184.26€ 175.49€ | |
| Viagra Generic | 200mg | 90 + 6 Pills | 170.79€ 162.66€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Viagra Generic | 150mg | 120 + 8 Pills | 177.58€ 169.12€ | |
| Viagra Generic | 200mg | 120 + 8 Pills | 204.80€ 195.05€ | |
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ | |
| Viagra Generic | 150mg | 60 + 4 Pills | 111.25€ 105.95€ | |
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Viagra Generic | 50mg | 30 + 4 Pills | 54.26€ 51.68€ | |
| Kamagra Polo | 100mg | 20 Pills | 83.56€ 79.58€ |
If it’s not treated right away, this condition can cause permanent damage to your penis. Sudden vision loss warning: This drug can cause sudden vision loss in one or both eyes. This can be a sign of a serious eye problem.
| Population | Recommendations | Cautions |
|---|---|---|
| Elderly | Start with lower doses | Monitor for side effects |
| Patients with Kidney Disease | Adjust dosage as needed | Increased risk of side effects |
| Patients with Liver Disease | Dose adjustment possible | Reduced metabolism, caution |
If this occurs, stop taking sildenafil and call your doctor right away. Sudden hearing loss warning: This drug can cause hearing loss, tinnitus (ringing in your ears), or dizziness.
8.4 Pediatric Use
For ED: Sildenafil works by increasing blood flow to the penis. This helps you get or maintain an erection. Sildenafil only works for ED if you’re sexually aroused. For PAH: Sildenafil works by relaxing the muscles and opening up the blood vessels in your lungs. This decreases the blood sildenafil citrate tablets for female pressure in your lungs. If you have sudden hearing loss with or without tinnitus or dizziness, stop taking sildenafil and call your doctor right away. Use in children warning: Children generally should not take sildenafil; however, there are instances where the drug is considered the best treatment option.
5.4 Visual Loss
Throw away the reconstituted oral suspension after 60 days. Active ingredient: sildenafil citrateInactive ingredients: dextrose and water for injection. Contains no ingredients made from gluten-containing grain (eg, wheat, barley, or rye). Revatio is distributed by Pfizer Labs, Division of Pfizer Inc., NY, NY 10017. Viagra is distributed by Pfizer Labs, Division of Pfizer Inc., NY, NY 10017.
Professional resources
It is distributed by: IBSA Pharma Inc, Parsippany, NJ 07054 USA. Cialis vs Viagra - What's the difference between them? Do you know these 11 amazing facts about Viagra? Is generic Viagra available in the U.S.? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Talk with your child’s doctor to better understand the benefits and risks associated with this treatment option. Sildenafil oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk with your doctor or pharmacist. Examples of drugs that can cause interactions with sildenafil are listed below. Do not take these drugs with sildenafil. Doing so can cause dangerous effects in the body. Nitrates, such as isosorbide mononitrate, isosorbide dinitrate, or nitroglycerin.Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level. Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level. Guanylate cyclase stimulators, such as riociguat.Taking these drugs with sildenafil can cause your blood pressure to drop suddenly to an unsafe level. Side effects from sildenafil: Taking sildenafil with certain medications raises your risk for side effects from sildenafil. This is because the amount of sildenafil in your body is increased. HIV drugs, such as ritonavir, indinavir, saquinavir, or atazanavir.Increased side effects can include low blood pressure, dizziness, or vision problems. They can also include erections that last longer than normal. Increased side effects can include low blood pressure, dizziness, or vision problems. Certain antibiotics, such as clarithromycin or erythromycin.Increased side effects can include low blood pressure, dizziness, or vision problems. Certain antifungals, such as ketoconazole or itraconazole.Increased side effects can include low blood pressure, dizziness, or vision problems. Side effects from other drugs: Taking sildenafil with certain medications raises your risk for side effects from these drugs.
Formats available
Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure Alpha-blockers are sometimes prescribed for prostate problems orhigh blood pressure. In some patients, the use of sildenafil with alpha-blockers can lead to a drop in blood pressure or fainting Other drugs to treat high blood pressure or a prostate disorder Medicines to treat HIV, such as protease inhibitors, such as ritonavir and saquinavir Some types of oral antifungal medicines, such as ketoconazole and itraconazole Some types of antibiotics, such as erythromycin Other medicines that treat high blood pressure Medicines or treatments for ED, such as avanafil (Stendra), tadalafil (Cialis), or vardenafil (Levitra). Tell your doctor about all other medications you use for erectile dysfunction. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure.
Does sildenafil interact with other medicines (drug interactions)?
Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine. Other drugs may interact with sildenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Store sildenafil tablets and oral film at room temperature, between 20°C and 25°C (68°F and 77°F). Store sildenafil reconstituted oral suspension below 30°C (86°F) or in a refrigerator between 2°C to 8°C (36°F to 46°F). Alpha-blockers, such as terazosin, tamsulosin, doxazosin, alfuzosin, or silodosin.Increased side effects can include a drop in blood pressure, or fainting.
What to avoid
Generic oral tablets are available for both conditions, but the brand-name drugs each treat only one of the conditions. Viagra: This drug is used to treat ED. With ED, you’re unable to get or maintain an erection. Revatio: This drug is used to treat PAH. With PAH, the blood pressure in your lungs is too high.
Warnings for people with certain health conditions
Your heart has to work very hard to pump blood into your lungs. Sildenafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Sildenafil works in different ways, depending on the condition it’s being used to treat. Increased side effects can include a drop in blood pressure, or fainting.
| Country | Status | Notes |
|---|---|---|
| USA | Approved by FDA | Prescription required |
| EU countries | Approved and regulated | Prescription necessary |
| Some developing countries | Varies; often available OTC | Legality depends on local laws |
Blood pressure drugs, such as amlodipine.Increased side effects can include blood pressure that’s too low. Increased side effects can include blood pressure that’s too low.
8.7 Patients with Renal Impairment
Sildenafil slows down the progression of your illness. It also makes you more able to exercise. Sildenafil can be used as early as 4 hours before sex and as late as 30 minutes before sex. However, it is recommended to use this drug within an hour before sex. Sildenafil should not be taken for ED more than once in a 24-hour period. Other drugs for erectile dysfunction, such as avanafil, tadalafil, or vardenafil.Increased side effects can include low blood pressure or erections that last longer than normal Increased side effects can include low blood pressure or erections that last longer than normal Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Sildenafil can cause a severe allergic reaction.
- Sildenafil tablets are available by prescription and should not be purchased from unverified sources.
- Store sildenafil tablets at room temperature away from moisture and heat.
- Do not split or crush sildenafil tablets unless specified by a doctor.
If you develop these symptoms, call 911 or go to the nearest emergency room.
