Open Surveys
^ Boolell M, Allen MJ, Ballard SA, Gepi-Attee S, Muirhead GJ, Naylor AM, et al. "Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction". "Sildenafil (Viagra), a potent and selective inhibitor of Type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction". "Drug repositioning: identifying and developing new uses for existing drugs". Archived from the original on 22 April 2019. Archived from the original on 10 June 2019. "Health situation in former communist bloc is dire, says Unicef". Archived from the original on 1 November 2012. ^ Gurevich M, Cormier N, Leedham U, Brown-Bowers A (August 2018). Sexuopharmaceutical use by men as prevention and proficiency". "Spreading the Word, but What Word is That? Viagra and Male Sexuality in Popular Culture". "A new view of women's sexual problems: Why new? Archived from the original on 3 January 2009. Archived from the original on 12 October 2008. "Sales of Impotence Drugs Fall, Defying Expectations". Archived from the original on 11 October 2007.
| Form | Description | Advantages |
|---|---|---|
| Tablets | Standard pill | Easy to dose, portable |
| Orally Disintegrating Tablets | Dissolves on tongue | No water needed, discreet |
| Liquid | Sildenafil solution | Easier for those with swallowing issues |
| Topical Gel | External application (experimental) | Potential local effects |
^ "Pfizer Courting More Controversy with Viagra 'Advergaming'". Archived from the original on 19 December 2019. Archived from the original on 6 May 2018. Archived from the original on 9 January 2009.
- Sildenafil may improve confidence and sexual satisfaction in men with ED.
- The medication is also being researched for pulmonary hypertension treatment.
- Common side effects include dizziness, upset stomach, and vision changes.
- Rare side effects can include priapism, a painful prolonged erection.
- Alcohol can interfere with sildenafil's effectiveness and increase side effects.
- Patients should disclose any heart conditions before using sildenafil.
- Sildenafil may interact with other medications such as alpha-blockers.
- It is not suitable for individuals with severe liver or kidney problems.
- Taking large doses does not necessarily improve efficacy and increases risk.
- Always follow the prescribed dosage and discontinue if adverse effects occur.
Archived from the original on 22 February 2021. ^ a b "Viagra now available over the counter without prescription in the UK".
Detection in biological fluids
"Phosphodiesterase inhibitors for erectile dysfunction in patients with diabetes mellitus". "Strategies for managing sexual dysfunction induced by antidepressant medication". The Cochrane Database of Systematic Reviews (5) CD003382. Archived from the original on 10 October 2020. "Efficacy and safety of sildenafil treatment in pulmonary arterial hypertension: a systematic review".
Sildenafil: what you need to know
Archived from the original on 29 August 2021. "Raynaud's phenomenon and digital ischaemia--pharmacologic approach and alternative treatment options". "Efficacy of Sildenafil on healthy humans in high‑altitude hypoxia at rest and during exercise: A meta‑analysis". "Interventions for preventing high altitude illness: Part 1. Archived from the original on 10 June 2017.
Storage and Handling
^ "FDA Updates Labeling for Viagra, Cialis and Levitra for Rare Post-Marketing Reports of Eye Problems" (Press release). Archived from the original on 22 October 2016. "Vision disorders and phosphodiesterase type 5 inhibitors: a review of the evidence to date". ^ "FDA Announces Revisions to Labels for Cialis, Levitra and Viagra". "Drug interactions with phosphodiesterase-5 inhibitors used for the treatment of erectile dysfunction or pulmonary hypertension". Archived from the original on 26 March 2021. Archived from the original on 8 December 2013.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Kamagra Polo | 100mg | 180 + 8 Pills | 446.52€ 425.26€ | |
| Viagra Generic | 150mg | 20 Pills | 55.02€ 52.40€ | |
| Viagra Generic | 150mg | 120 + 8 Pills | 177.58€ 169.12€ | |
| Kamagra Polo | 100mg | 12 Pills | 60.21€ 57.34€ | |
| Viagra Generic | 200mg | 180 + 10 Pills | 277.56€ 264.34€ | |
| Viagra Generic | 150mg | 270 + 10 Pills | 326.61€ 311.06€ | |
| Kamagra Soft Tabs | 100mg | 180 + 8 Pills | 425.45€ 405.19€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Viagra Generic | 150mg | 30 + 2 Pills | 72.32€ 68.88€ | |
| Kamagra Soft Tabs | 100mg | 60 + 4 Pills | 180.59€ 171.99€ | |
| Viagra Generic | 200mg | 10 Pills | 40.96€ 39.01€ | |
| Kamagra Oral Jelly | 100mg | 220 + 18 Sachets | 662.24€ 630.70€ | |
| Viagra Generic | 50mg | 120 + 6 Pills | 129.64€ 123.47€ |
"The coming generics threat to Pfizer's Viagra brand just got scarier". Archived from the original on 9 September 2017. ^ "Viagra to go generic in 2017 according to Pfizer agreement". Archived from the original on 1 December 2017. "Sex, Drugs and That Little Blue Pill".
- Do not take sildenafil if you have a history of heart attack or stroke.
- Women and children should not use sildenafil products.
- The medication can cause temporary vision disturbances, including blue-tinted vision.
- Always consult a healthcare provider before starting sildenafil therapy.
- Use caution when driving or operating machinery after taking sildenafil.
- Sildenafil is contraindicated in people with hypersensitivity to the drug.
- Some users report improved erectile function within 15 minutes.
- It is essential to stay hydrated, but avoid consuming large amounts of alcohol.
- Men with certain health conditions should undergo a medical exam before use.
- Overuse or misuse of sildenafil can lead to serious health complications.
Archived from the original on 6 December 2017. "Why Pfizer Is About to Slash Viagra's Price in Half". Archived from the original on 7 December 2017. "Pfizer to lose patent of drug Viagra, Indian companies gear up with copycat versions: Pfizer's patent for the formulation of Viagra, used to treat impotence in men, ends in the US in 2020". Archived from the original on 17 April 2021.
| Brand Name | Manufacturer | Price Range (per pill) | Availability | Notes |
|---|---|---|---|---|
| Viagra | Pfizer | $10 - $30 | Widely available | Most popular brand |
| Kamagra | Ajanta Pharma | $2 - $8 | Online, some stores | Cheaper alternative |
| Sildenafil Citrate | Generic | $1 - $5 | Online, pharmacies | Generic form available |
^ "Set to conquer US, Indian 'Viagras' may give Pfizer a hard Time". Archived from the original on 22 December 2020. ^ a b "Pfizer Settles Viagra® Patent Litigation With Teva". "Lockout Supplements Issues Voluntary Nationwide Recall of Boner Bears Chocolate Syrup Due to Undeclared Sildenafil". Archived from the original on 19 November 2016.
How should I take sildenafil?
Archived from the original on 14 January 2023. "Sildenafil: from angina to erectile dysfunction to pulmonary hypertension and beyond". Archived from the original on 26 September 2008. Our clinicians regularly offer patients the opportunity to take part in trials of new drugs and treatments. Morriston Hospital in Swansea, was the first in the world to trial Viagra! "Counterfeit Viagra, Cialis, Levitra: The Ultimate Guide". Archived from the original on 10 January 2017. "Online pharmacies suspected of counterfeit drug sales". ^ "Erectile Dysfunction Medication the Most Seized Drug During Global Crackdown, Interpol Says".
| Age Range | Suitability | Notes |
|---|---|---|
| 18-50 years | Usually suitable | Under doctor supervision |
| 51-70 years | Caution advised | Dose adjustment may be needed |
| Over 70 years | Use with caution | Potential drug interactions |
^ "Global illicit medicines targeted by INTERPOL operation". Archived from the original on 10 December 2023. ^ "Israeli-made AI exposes international fake Viagra network". ^ "Counterfeit Viagra Pills, Footwear, Belts, Car Emblems and Headphones Worth over $32 Million Seized at the LA/Long Beach Seaport U.S. Customs and Border Protection". Archived from the original on 12 October 2013. "Yes, There Is a Way to Get Generic Viagra". Archived from the original on 2 May 2016. "Pfizer Wins Viagra Patent Infringement Case Against Teva Pharmaceuticals". Archived from the original on 11 January 2015.
In case of emergency/overdose
"Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions". Use of sildenafil (Viagra) in patients with cardiovascular disease. American College of Cardiology/American Heart Association". Journal of the American College of Cardiology. ^ "Viagra (Sildenafil Citrate): Side Effects, Interactions, Warning, Dosage & Uses".
Incidence not known
Archived from the original on 12 July 2018. "Young men add Viagra to their drug arsenal". Archived from the original on 4 September 2014. "Recreational use and misuse of phosphodiesterase 5 inhibitors". Archived from the original on 21 August 2016.
Sildenafil: the science
"Sildenafil does not improve sexual function in men without erectile dysfunction but does reduce the postorgasmic refractory time". ^ McCambridge J, Mitcheson L, Hunt N, Winstock A (March 2006). "The rise of Viagra among British illicit drug users: 5-year survey data". "Does marijuana use play a role in the recreational use of sildenafil?". Archived from the original on 26 January 2013. ^ "Pfizer Completes Transaction to Combine Its Upjohn Business with Mylan". Retrieved 17 June 2024 – via Business Wire. Archived from the original on 17 chew sildenafil June 2024. "Viagra patent expires in June, says Brazilian court". Archived from the original on 17 April 2012. ^ "Revatio patent ruled invalid for lack of sound prediction and obviousness".
- Sildenafil is a medication used to treat erectile dysfunction in men.
- It works by increasing blood flow to the penis during arousal.
- Sildenafil is commonly sold under the brand name Viagra.
- The typical dose ranges from 25 mg to 100 mg, taken before sexual activity.
- It usually takes about 30 to 60 minutes to work after ingestion.
- Sildenafil's effects can last for up to 4-6 hours.
- It can cause side effects like headaches, flushing, and nasal congestion.
- Sildenafil should not be used with nitrate medications due to risk of dangerous drops in blood pressure.
- It is available by prescription from a healthcare provider.
- Do not take sildenafil more than once a day to avoid adverse effects.
Archived from the original on 3 March 2016. {{cite web}}: CS1 maint: deprecated archival service (link) ^ Teva Canada Ltd. v. Pfizer Canada Inc., 2012 SCC 60 at par. "Supreme Court ruling could lead to cheaper versions of Viagra". Archived from the original on 10 March 2013. "Canadian Supreme court rules Viagra patent invalid".
Why is this medication prescribed?
Baselt, Disposition of Toxic Drugs and Chemicals in Man, 9th edition, Biomedical Publications, Seal Beach, CA, 2011, pp. Archived from the original (PDF) on 10 September 2011. "Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules". ^ a b Webb DJ, Freestone S, Allen MJ, Muirhead GJ (March 1999). "Sildenafil citrate and blood-pressure-lowering drugs: results of drug interaction studies with an organic nitrate and a calcium antagonist".
Vitamin K Antagonists
^ Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA (May 1998). "Oral sildenafil in the treatment of erectile dysfunction. Archived from the original on 14 January 2012. "Onset and duration of action of sildenafil for the treatment of erectile dysfunction". ^ "Scientist who developed Viagra receives knighthood in New Year's Honours". Archived from the original on 11 November 2012. ^ "Viagra patent tossed out by Supreme Court: Decision allows generic versions of drug to be produced". Archived from the original on 18 September 2013. ^ "Pfizer Canada drops Viagra price after generic versions get Supreme Court green light". Archived from the original on 30 November 2012. Archived from the original on 27 December 2013. "In rare move, Pfizer asks Supreme Court to reconsider ruling that killed Viagra patent". Archived from the original on 5 February 2013. "The Supreme Court of Canada holds Pfizer's Viagra patent invalid". Archived from the original on 20 May 2013. ^ "Actavis Launches Generic Viagra in Europe as Patents Expire". Archived from the original on 29 October 2013. "What Will Happen When Viagra Goes Generic?". Archived from the original on 23 April 2011.
- Sildenafil can sometimes cause flushing and nasal congestion.
- It is not a cure for erectile dysfunction, only a treatment option.
- Psychological factors can also affect erectile performance alongside medication.
- Sildenafil may sometimes interact with foods that contain high fat content.
- Regular exercise and stress management can complement treatment with sildenafil.
- The medication should be stored safely out of children's reach.
- Reporting side effects to a healthcare provider is important for safety.
- Sildenafil is typically started at a low dose, gradually increased if needed.
- It is important to follow the prescribed timing for medication intake.
- Discontinuing sildenafil should be discussed with a healthcare professional.
^ "Is Viagra about to lose its pulling power in the UK?". Archived from the original on 30 October 2013. Archived from the original on 22 August 2009. Archived from the original on 25 June 2007. "Viagra from the pharmacist: insight from reclassification in New Zealand". Archived from the original on 17 May 2021. ^ "Generic Viagra developers queue up, but may have to wait". Archived from the original on 28 December 2021. ^ "Approved Viagra copies flood drugstores in Korea".
Warnings & Precautions
"Sildenafil accelerates reentrainment of circadian rhythms after advancing light schedules". Proceedings of the National Academy of Sciences of the United States of America. "Source: Roger Clemens, host of athletes pop Viagra to help onfield performance". Archived from the original on 14 August 2020. "Bears' Brandon Marshall says some NFL players use Viagra ..
Are there reviews from people who had side effects with 50-mg or 100-mg sildenafil tablets?
on the Field". Archived from the original on 5 March 2016. "Towards a decade of detecting new analogues of sildenafil, tadalafil and vardenafil in food supplements: a history, analytical aspects and health risks". "Detection of sildenafil analogues in herbal products sildenafil 100mg hexal for erectile dysfunction". Archived from the original on 4 March 2016.
Sildenafil 20 mg Dosage for Erectile Dysfunction
^ "FDA Warns Consumers About Dangerous Ingredients in "Dietary Supplements" Promoted for Sexual Enhancement". Archived from the original on 18 January 2017. ^ "Hidden Risks of Erectile Dysfunction 'Treatments' Sold Online". Archived from the original on 23 April 2019. ^ R. ^ "Viagra prescriptions almost triple in a decade". Archived from the original on 1 July 2024. ^ "MHRA reclassifies Viagra Connect tablets to a Pharmacy medicine". ^ "Viagra to be available without prescription in UK". Sildenafil is one of the best-known medications for managing erectile dysfunction (ED) — and not just because it was the first erectile dysfunction drug on the scene back in 1998.
